Mpox

It is important for residents to recognize the symptoms of mpox (formerly called monkeypox) and know how to prevent getting it.

Overview

Mpox is a disease caused by the mpox virus. It is typically spread through close physical contact. There are two clades of Mpox: Clade I and Clade II. Clade II is circulating at low levels in the United States, and Clade I is endemic in Western, Central and Eastern Africa. 

The virus often causes a painful rash, which may look like bumps on your skin, blisters, or ulcers. Some people have a flu-like illness before they develop a rash. Infections with the type of mpox virus identified in the U.S. are rarely fatal, and most people recover in 2–4 weeks.

National data suggest that gay, bisexual, and other men who have sex with men made up the majority of cases in the recent mpox outbreak in the United States.  However, anyone regardless of sexual orientation or gender identity, who has been in close contact with someone who has mpox is at risk. There is also a current risk for Clade I associated with travel to outbreak areas.

How Mpox Spreads

Mpox is usually spread from one person to another through close, often skin-to skin contact. See the most current information on how mpox spreads from the CDC.

How to Lower Your Risk

Testing

If you have any symptoms of mpox, talk to your health care provider, even if you don’t think you have had contact with someone who has mpox.

If you do not have a provider, you can:

  • Contact the Cambridge Public Health Department for guidance: 617-665-3800 (press 8).  
  • Register to become a Cambridge Health Alliance patient: 617-665-1305.

While you are waiting for your test results, you should isolate at home and follow this guidance from the CDC.

Mpox Vaccine

The CDC recommends vaccination for people who have been exposed to mpox and people who are at higher risk of being exposed to mpox. 

To find out where you can get vaccinated, see the Massachusetts Department of Public Health’s list of mpox vaccine providers. 

Treatment

There are several treatment options to improve the symptoms of mpox, including antiviral treatment and supportive care. We recommend that residents infected with mpox reach out to their health care provider to discuss these options to ensure they are safe and appropriate.  

More Information

Data

Cambridge Cases
5-10 mpox cases have been reported in Cambridge residents between May–November 2022. See Cambridge Case Data.

Massachusetts and U.S. 
For state and national data, visit the CDC’s U.S. Case Count page.

Updated: November 14, 2025