To receive a Laboratory Biosafety permit, every new applicant must present to the Cambridge Biosafety Committee. The presentation must include:

  1. Street address of the proposed facility or facilities. Please include a specific floor or suite within the building.
  2. Total floor area of biological laboratory space (estimate is OK) and proposed biological containment level(s) or biological safety levels (BSL).
  3. A summary of research or manufacturing activities and agents, organized by Risk Group as determined by the Institutional Biosafety Committee for the applicant.
  4. A floor plan indicating all laboratory areas, biological containment levels or BSL(s), waste storage location and pathway for removal, doors, and exits.
  5. Documentation of a medical surveillance agreement with a local occupational health provider or an in-house clinical provider.
  6. Documentation showing that an air balance was conducted to document a steady negative airflow into any BSL-2 lab areas.
  7. Summary of compliance status for all local and state health and safety regulations requiring permits (e.g., flammable storage and cryogenic gas permit, DEP VSQG or SQG chem waste permit, state radiation permit, MWRA wastewater permit).
  8. A list of vendors that support the safe operation of the laboratory.

Presentations generally last 20 to 45 minutes, and should provide a broad explanation of the recombinant technologies, risk of infection, biological vectors, and host organisms being used. For an example, see our sample presentation. For more information, please view the Cambridge Biosafety Committee’s Policies and Procedures.

Updated: August 26, 2022